Dichloromethane → Chloro-4-morpholino-6-nitro-pyrido[2,3-d]pyrimidine

HRID 215122Notes

Reaction equation

HRID 215122 reaction equation
[CH2:16]1[CH2:17][O:18][CH2:19][CH2:20][NH:21]1.[CH:22]([N:23]([CH:24]([CH3:25])[CH3:26])[CH2:27][CH3:28])([CH3:29])[CH3:30].[Cl:1][c:2]1[n:3][c:4]([Cl:15])[c:5]2[c:6]([n:7]1)[n:8][cH:9][c:10]([N+:12](=[O:13])[O-:14])[cH:11]2.[Cl:31][CH2:32][Cl:33]>>[Cl:1][c:2]1[n:3][c:4]([N:21]2[CH2:16][CH2:17][O:18][CH2:19][CH2:20]2)[c:5]2[c:6]([n:7]1)[n:8][cH:9][c:10]([N+:12](=[O:13])[O-:14])[cH:11]2

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 8083MorpholineHCID 81531DiisopropylethylamineHCID 860497362,4-Dichloro-6-nitro-pyrido[2,3-d]pyrimidine

Product 1

HCID 57935891Chloro-4-morpholino-6-nitro-pyrido[2,3-d]pyrimidine

Sources & evidence

ORD record
ord-827ab40db30945c9be7cbbfe8549de4c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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