2-Methylpyrrolidine → 1-[2-(6-Bromo-naphthalen-2-yl)-ethyl]-2-methyl-pyrrolidine
Reaction equation
[Br:1][c:2]1[cH:3][c:4]2[c:5]([cH:6][cH:7]1)[cH:8][c:9]([O:10][S:11]([C:12]([F:13])([F:14])[F:15])(=[O:16])=[O:17])[cH:18][cH:19]2.[Br:20][c:21]1[cH:22][c:23]2[cH:24][cH:25][c:26]([CH:31]=[CH2:32])[cH:27][c:28]2[cH:29][cH:30]1.[CH2:39]([Li:40])[CH2:41][CH2:42][CH3:43].[CH3:33][CH:34]1[NH:35][CH2:36][CH2:37][CH2:38]1>>[Br:20][c:21]1[cH:22][c:23]2[cH:24][cH:25][c:26]([CH2:31][CH2:32][N:35]3[CH:34]([CH3:33])[CH2:38][CH2:37][CH2:36]3)[cH:27][c:28]2[cH:29][cH:30]1Participants
5
Sources & evidence
- ORD record
- ord-2c269dcfad0b4775b334193310904a7e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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