Sodium ion → 3-(2-Fluoro-4-iodo-phenylamino)-thieno[2,3-c]pyridine-2-carboxylic acid ethyl ester

HRID 2151348Notes

Reaction equation

HRID 2151348 reaction equation
[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[c:6]1[c:7]([NH:15][c:16]2[c:17]([F:23])[cH:18][c:19]([Br:22])[cH:20][cH:21]2)[c:8]2[c:9]([cH:10][n:11][cH:12][cH:13]2)[s:14]1.[CH2:26]1[O:27][CH2:28][CH2:29][O:30][CH2:31]1.[Cu:32].[Cu:33][I:34].[I-:25].[Na+:24]>>[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[c:6]1[c:7]([NH:15][c:16]2[c:17]([F:23])[cH:18][c:19]([I:25])[cH:20][cH:21]2)[c:8]2[c:9]([cH:10][n:11][cH:12][cH:13]2)[s:14]1

Participants

7

Reactant 6

HCID 923Sodium ionHCID 23978CopperHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 30165Iodide IonHCID 312751,4-DioxaneHCID 59703899Ethyl 3-(4-bromo-2-fluoro-phenylamino)-thieno[2,3-c]pyridine-2-carboxylate

Product 1

HCID 597039023-(2-Fluoro-4-iodo-phenylamino)-thieno[2,3-c]pyridine-2-carboxylic acid ethyl ester

Sources & evidence

ORD record
ord-224e15dae087498ea57d710b315f6f55
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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