Acetonitrile → 3-[7-[[4-[[4-(3-methylphenyl)piperidin-1-yl]methyl]phenyl]methoxy]-3-oxo-1H-isoindol-2-yl]piperidine-2,6-dione
Reaction equation
[Br:4][CH2:5][c:6]1[cH:7][cH:8][c:9]([CH2:10][O:11][c:12]2[c:13]3[c:17]([cH:18][cH:19][cH:20]2)[C:16](=[O:21])[N:15]([CH:22]2[C:23](=[O:29])[NH:24][C:25](=[O:28])[CH2:26][CH2:27]2)[CH2:14]3)[cH:30][cH:31]1.[CH2:45]([N:46]([CH:47]([CH3:48])[CH3:49])[CH:50]([CH3:51])[CH3:52])[CH3:53].[CH2:54]([Cl:55])[Cl:56].[CH3:1][C:2]#[N:3].[c:32]1([CH3:44])[cH:33][c:34]([CH:38]2[CH2:39][CH2:40][NH:41][CH2:42][CH2:43]2)[cH:35][cH:36][cH:37]1>>[CH2:5]([c:6]1[cH:7][cH:8][c:9]([CH2:10][O:11][c:12]2[c:13]3[c:17]([cH:18][cH:19][cH:20]2)[C:16](=[O:21])[N:15]([CH:22]2[C:23](=[O:29])[NH:24][C:25](=[O:28])[CH2:26][CH2:27]2)[CH2:14]3)[cH:30][cH:31]1)[N:41]1[CH2:40][CH2:39][CH:38]([c:34]2[cH:33][c:32]([CH3:44])[cH:37][cH:36][cH:35]2)[CH2:43][CH2:42]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-f7f347750ee942988312872a96770ed3
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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