Acetonitrile → ethyl 3-(2,3-dihydro-1H-spiro[isoquinoline-4,4'-piperidine]-1'-yl)-8-azabicyclo[3.2.1]octane-8-carboxylate
Reaction equation
[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[N:6]1[CH:7]2[CH2:8][CH:9]([N:14]3[CH2:15][CH2:16][C:17]4([CH2:18][N:19]([C:27]([O:28][C:29]([CH3:30])([CH3:31])[CH3:32])=[O:33])[CH2:20][c:21]5[cH:22][cH:23][cH:24][cH:25][c:26]54)[CH2:34][CH2:35]3)[CH2:10][CH:11]1[CH2:12][CH2:13]2.[CH3:46][C:47]#[N:48].[Cl:43][CH2:44][Cl:45].[OH:36][C:37]([C:38]([F:39])([F:40])[F:41])=[O:42]>>[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[N:6]1[CH:7]2[CH2:8][CH:9]([N:14]3[CH2:15][CH2:16][C:17]4([CH2:18][NH:19][CH2:20][c:21]5[cH:22][cH:23][cH:24][cH:25][c:26]54)[CH2:34][CH2:35]3)[CH2:10][CH:11]1[CH2:12][CH2:13]2Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-bb8f1487743a47b6b53240a7488ee423
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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