Sodium ion → 2,4-Difluoro-1,1'-biphenyl

HRID 2151983Notes

Reaction equation

HRID 2151983 reaction equation
[Br:12][c:13]1[cH:14][cH:15][cH:16][cH:17][cH:18]1.[CH3:25][O:26][CH2:27][CH2:28][O:29][CH3:30].[F:1][c:2]1[c:3]([B:9]([OH:10])[OH:11])[cH:4][cH:5][c:6]([F:8])[cH:7]1.[Na+:19].[Na+:20].[O-:21][C:22](=[O:23])[O-:24].[OH2:31]>>[F:1][c:2]1[c:3](-[c:13]2[cH:14][cH:15][cH:16][cH:17][cH:18]2)[cH:4][cH:5][c:6]([F:8])[cH:7]1

Participants

7

Reactant 6

HCID 923Sodium ion2×HCID 962WaterHCID 7961BromobenzeneHCID 80711,2-DimethoxyethaneHCID 19660Carbonate IonHCID 27343342,4-Difluorophenylboronic acid

Product 1

HCID 1699742,4-Difluoro-1,1'-biphenyl

Sources & evidence

ORD record
ord-b3fe680291e04a9eb8de28dff503d176
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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