Dichloromethane → 1-(4-tert-Butylphenyl)-3-(4-(hydroxymethyl)phenyl)imidazolidin-2-one

HRID 2152138Notes

Reaction equation

HRID 2152138 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[c:5]1[cH:6][cH:7][c:8]([N:11]2[C:12](=[O:26])[N:13]([c:16]3[cH:17][cH:18][c:19]([C:20](=[O:21])[O:22][CH3:23])[cH:24][cH:25]3)[CH2:14][CH2:15]2)[cH:9][cH:10]1.[CH3:27][CH:28]([CH2:29][AlH:30][CH2:31][CH:32]([CH3:33])[CH3:34])[CH3:35].[Cl:36][CH2:37][Cl:38]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[c:5]1[cH:6][cH:7][c:8]([N:11]2[C:12](=[O:26])[N:13]([c:16]3[cH:17][cH:18][c:19]([CH2:20][OH:21])[cH:24][cH:25]3)[CH2:14][CH2:15]2)[cH:9][cH:10]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 14487Diisobutylaluminum hydrideHCID 59456842Methyl 4-(3-(4-tert-butylphenyl)-2-oxoimidazolidin-1-yl)benzoate

Product 1

HCID 594568851-(4-tert-Butylphenyl)-3-(4-(hydroxymethyl)phenyl)imidazolidin-2-one

Sources & evidence

ORD record
ord-c032fe4588884f708dede7e95afeed15
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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