Tetrahydrofuran → 4-(2-Aminomethyl-3-benzylamino-6-fluoro-phenyl)-piperazine-1-carboxylic acid tert-butyl ester
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][N:11]([c:14]2[c:15]([C:29]#[N:30])[c:16]([NH:21][CH2:22][c:23]3[cH:24][cH:25][cH:26][cH:27][cH:28]3)[cH:17][cH:18][c:19]2[F:20])[CH2:12][CH2:13]1.[O:31]1[CH2:32][CH2:33][CH2:34][CH2:35]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][N:11]([c:14]2[c:15]([CH2:29][NH2:30])[c:16]([NH:21][CH2:22][c:23]3[cH:24][cH:25][cH:26][cH:27][cH:28]3)[cH:17][cH:18][c:19]2[F:20])[CH2:12][CH2:13]1Participants
3
Sources & evidence
- ORD record
- ord-78280aa1f1174028bf7bc7af034366f8
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
Loading…