Tetrahydrofuran → 5-azido-4-chloro-1-(triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridine
Reaction equation
[CH2:39]1[O:40][CH2:41][CH2:42][CH2:43]1.[CH:21]([Li:22])([CH2:23][CH3:24])[CH3:25].[Cl:1][c:2]1[c:3]2[c:4]([n:5][cH:6][cH:7]1)[n:8]([Si:11]([CH:12]([CH3:13])[CH3:14])([CH:15]([CH3:16])[CH3:17])[CH:18]([CH3:19])[CH3:20])[cH:9][cH:10]2.[S:26]([c:27]1[cH:28][cH:29][c:30]([CH3:31])[cH:32][cH:33]1)(=[O:34])(=[O:35])[N:36]=[N+:37]=[N-:38]>>[Cl:1][c:2]1[c:3]2[c:4]([n:5][cH:6][c:7]1[N:36]=[N+:37]=[N-:38])[n:8]([Si:11]([CH:12]([CH3:13])[CH3:14])([CH:15]([CH3:16])[CH3:17])[CH:18]([CH3:19])[CH3:20])[cH:9][cH:10]2Participants
5
Sources & evidence
- ORD record
- ord-8a82c0c854944bff97ca82d036e876b0
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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