Dichloromethane → Piperidin-4-yl(2-(trifluoromethyl)phenyl)methanone

HRID 215343Notes

Reaction equation

HRID 215343 reaction equation
[C:1]([O:2][C:3](=[O:4])[N:8]1[CH2:9][CH2:10][CH:11]([C:14]([c:15]2[c:16]([C:21]([F:22])([F:23])[F:24])[cH:17][cH:18][cH:19][cH:20]2)=[O:25])[CH2:12][CH2:13]1)([CH3:5])([CH3:6])[CH3:7].[Cl:33][CH2:34][Cl:35].[OH:26][C:27]([C:28]([F:29])([F:30])[F:31])=[O:32]>>[NH:8]1[CH2:9][CH2:10][CH:11]([C:14]([c:15]2[c:16]([C:21]([F:22])([F:23])[F:24])[cH:17][cH:18][cH:19][cH:20]2)=[O:25])[CH2:12][CH2:13]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 585398564-(2-Trifluoromethylbenzoyl)piperidine-1-carboxylic acid tert-butyl ester

Product 1

HCID 16244270Piperidin-4-yl(2-(trifluoromethyl)phenyl)methanone

Sources & evidence

ORD record
ord-cddf13252b4e40ddb2da164c1fc56f73
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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