Water → 5-{[2-([Ethylsulfanyl]methyl)-1-(2-fluoro-4-methoxyphenyl)-3,3,3-trifluoro-2-hydroxypropyl]amino}-1H-quinolin-2-one
Reaction equation
[C:30](=[O:31])([O-:32])[O-:33].[CH2:36]([CH3:37])[SH:38].[Cs+:34].[Cs+:35].[F:1][c:2]1[c:3]([CH:10]([C:11]2([C:14]([F:15])([F:16])[F:17])[O:12][CH2:13]2)[NH:18][c:19]2[c:20]3[cH:21][cH:22][c:23](=[O:29])[nH:24][c:25]3[cH:26][cH:27][cH:28]2)[cH:4][cH:5][c:6]([O:8][CH3:9])[cH:7]1.[O:40]=[CH:41][N:42]([CH3:43])[CH3:44].[OH2:39]>>[F:1][c:2]1[c:3]([CH:10]([C:11]([OH:12])([CH2:13][S:38][CH2:36][CH3:37])[C:14]([F:15])([F:16])[F:17])[NH:18][c:19]2[c:20]3[cH:21][cH:22][c:23](=[O:29])[nH:24][c:25]3[cH:26][cH:27][cH:28]2)[cH:4][cH:5][c:6]([O:8][CH3:9])[cH:7]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-b4399212b2e64518bc5a02cc53aad7dc
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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