Tetrahydrofuran → 7-Bromo-2-methoxypyrazolo[1,5-a]pyridine

HRID 2153585Notes

Reaction equation

HRID 2153585 reaction equation
[Br:17][C:18]([Cl:19])([Cl:20])[C:21]([Br:22])([Cl:23])[Cl:24].[CH2:12]([Li:13])[CH2:14][CH2:15][CH3:16].[CH3:1][O:2][c:3]1[n:4][n:5]2[c:6]([cH:7][cH:8][cH:9][cH:10]2)[cH:11]1.[CH3:30][CH2:31][CH2:32][CH2:33][CH2:34][CH3:35].[O:25]1[CH2:26][CH2:27][CH2:28][CH2:29]1>>[CH3:1][O:2][c:3]1[n:4][n:5]2[c:6]([cH:7][cH:8][cH:9][c:10]2[Br:17])[cH:11]1

Participants

6

Reactant 5

HCID 8028TetrahydrofuranHCID 8058HexaneHCID 694261,2-Dibromo-1,1,2,2-tetrachloroethaneHCID 122844272-Methoxypyrazolo[1,5-a]pyridineHCID 178418339Butyllithium

Product 1

HCID 219846587-Bromo-2-methoxypyrazolo[1,5-a]pyridine

Sources & evidence

ORD record
ord-f1716a489a604438af5e8478105c6f3b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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