Hydrochloric Acid → (9-(4-(2-Hydroxyethyl)phenethyl)-1-oxa-4,9-diazaspiro[5.5]undecan-4-yl)(2-methylthiazol-4-yl)methanone

HRID 2153696Notes

Reaction equation

HRID 2153696 reaction equation
[C:2]([Si:3]([CH3:4])([CH3:5])[O:7][CH2:8][CH2:9][c:10]1[cH:11][cH:12][c:13]([CH2:14][CH2:15][N:16]2[CH2:17][CH2:18][C:19]3([CH2:20][N:21]([C:25](=[O:26])[c:27]4[n:28][c:29]([CH3:32])[s:30][cH:31]4)[CH2:22][CH2:23][O:24]3)[CH2:33][CH2:34]2)[cH:35][cH:36]1)([CH3:6])([CH3:37])[CH3:38].[CH3:39][OH:40].[ClH:1]>>[OH:7][CH2:8][CH2:9][c:10]1[cH:11][cH:12][c:13]([CH2:14][CH2:15][N:16]2[CH2:17][CH2:18][C:19]3([CH2:20][N:21]([C:25](=[O:26])[c:27]4[n:28][c:29]([CH3:32])[s:30][cH:31]4)[CH2:22][CH2:23][O:24]3)[CH2:33][CH2:34]2)[cH:35][cH:36]1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 887MethanolHCID 57989178(9-(4-(2-(tert-Butyldimethylsilyloxy)ethyl)phenethyl)-1-oxa-4,9-diazaspiro[5.5]undecan-4-yl)(2-methylthiazol-4-yl)methanone

Product 1

HCID 57989159(9-(4-(2-Hydroxyethyl)phenethyl)-1-oxa-4,9-diazaspiro[5.5]undecan-4-yl)(2-methylthiazol-4-yl)methanone

Sources & evidence

ORD record
ord-cd736f74937d45c096b49fec57db6219
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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