Ethanol → 5-[4-(3-methoxy-phenyl) 2-oxo-1,2-dihydro-indol-3-ylidenemethyl]-2,4-dimethyl-1H-pyrrole-3-carboxylic acid (2-diisopropylamino-ethyl)-amide

HRID 2153778Notes

Reaction equation

HRID 2153778 reaction equation
[CH2:40]1[CH2:41][CH2:42][NH:43][CH2:44][CH2:45]1.[CH3:1][O:2][c:3]1[cH:4][c:5](-[c:9]2[c:10]3[c:14]([cH:15][cH:16][cH:17]2)[NH:13][C:12](=[O:18])[CH2:11]3)[cH:6][cH:7][cH:8]1.[CH3:46][CH2:47][OH:48].[CH:19]([CH3:20])([CH3:21])[N:22]([CH2:23][CH2:24][NH:25][C:26](=[O:27])[c:28]1[c:29]([CH3:36])[nH:30][c:31]([CH:34]=[O:35])[c:32]1[CH3:33])[CH:37]([CH3:38])[CH3:39]>>[CH3:1][O:2][c:3]1[cH:4][c:5](-[c:9]2[c:10]3[c:14]([cH:15][cH:16][cH:17]2)[NH:13][C:12](=[O:18])[C:11]3=[CH:34][c:31]2[nH:30][c:29]([CH3:36])[c:28]([C:26]([NH:25][CH2:24][CH2:23][N:22]([CH:19]([CH3:20])[CH3:21])[CH:37]([CH3:38])[CH3:39])=[O:27])[c:32]2[CH3:33])[cH:6][cH:7][cH:8]1

Participants

5

Reactant 4

HCID 702EthanolHCID 8082PiperidineHCID 207617895-formyl-2,4-dimethyl-1 H-pyrrole-3-carboxylic acid (2-diisopropylamino-ethyl)-amideHCID 225618094-(3-Methoxy-phenyl)-1,3-dihydro indol-2-one

Product 1

HCID 249413505-[4-(3-methoxy-phenyl) 2-oxo-1,2-dihydro-indol-3-ylidenemethyl]-2,4-dimethyl-1H-pyrrole-3-carboxylic acid (2-diisopropylamino-ethyl)-amide

Sources & evidence

ORD record
ord-b5ddb8c6e9a648769d6d62e23abe518d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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