Water → 3-bromo-8-(cyclopentyloxy)-4-(3,5-dichloropyridin-4-ylamino)-7-methoxyquinolin-2(1H)-one
Reaction equation
[Br:1][N:2]1[C:3](=[O:4])[CH2:5][CH2:6][C:7]1=[O:8].[CH:9]1([O:14][c:15]2[c:16]([O:35][CH3:36])[cH:17][cH:18][c:19]3[c:20]([NH:26][c:27]4[c:28]([Cl:34])[cH:29][n:30][cH:31][c:32]4[Cl:33])[cH:21][c:22](=[O:25])[nH:23][c:24]23)[CH2:10][CH2:11][CH2:12][CH2:13]1.[O:37]=[CH:38][N:39]([CH3:40])[CH3:41].[OH2:42]>>[Br:1][c:21]1[c:20]([NH:26][c:27]2[c:28]([Cl:34])[cH:29][n:30][cH:31][c:32]2[Cl:33])[c:19]2[cH:18][cH:17][c:16]([O:35][CH3:36])[c:15]([O:14][CH:9]3[CH2:10][CH2:11][CH2:12][CH2:13]3)[c:24]2[nH:23][c:22]1=[O:25]Participants
5
Sources & evidence
- ORD record
- ord-afa7b4bf8b3a42d18babe9678bd0fd26
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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