Dichloromethane → 3-(4-Amino-3-methoxyphenyl)-7-iodofuro[3,2-c]pyridin-4-amine

HRID 2154155Notes

Reaction equation

HRID 2154155 reaction equation
[Cl:35][CH2:36][Cl:37].[NH2:1][c:2]1[n:3][cH:4][c:5]([I:27])[c:6]2[c:7]1[c:8](-[c:11]1[cH:12][c:13]([O:25][CH3:26])[c:14]([NH:17][C:18](=[O:19])[O:20][C:21]([CH3:22])([CH3:23])[CH3:24])[cH:15][cH:16]1)[cH:9][o:10]2.[OH:28][C:29]([C:30]([F:31])([F:32])[F:33])=[O:34]>>[NH2:1][c:2]1[n:3][cH:4][c:5]([I:27])[c:6]2[c:7]1[c:8](-[c:11]1[cH:12][c:13]([O:25][CH3:26])[c:14]([NH2:17])[cH:15][cH:16]1)[cH:9][o:10]2

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 18451460Tert-butyl 4-(4-amino-7-iodofuro[3,2-c]pyridin-3-yl)-2-methoxyphenylcarbamate

Product 1

HCID 184507093-(4-Amino-3-methoxyphenyl)-7-iodofuro[3,2-c]pyridin-4-amine

Sources & evidence

ORD record
ord-0a3e01a8992948e8a07f5b575f243d28
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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