Tetrahydrofuran → N,N-diisobutyl-1-{3-[methyl(2-pyridin-2-ylethyl)amino]propyl}-2-{[2-oxo-2-(3,4,5-trimethoxyphenyl)ethyl]thio}-1H-benzimidazole-5-carboxamide
Reaction equation
[Br:1][CH2:2][C:3](=[O:4])[c:5]1[cH:6][c:7]([O:15][CH3:16])[c:8]([O:13][CH3:14])[c:9]([O:11][CH3:12])[cH:10]1.[CH2:17]([CH:18]([CH3:19])[CH3:20])[N:21]([C:22](=[O:23])[c:24]1[cH:25][c:26]2[c:27]([n:28]([CH2:32][CH2:33][CH2:34][N:35]([CH2:36][CH2:37][c:38]3[n:39][cH:40][cH:41][cH:42][cH:43]3)[CH3:44])[c:29](=[S:31])[nH:30]2)[cH:45][cH:46]1)[CH2:47][CH:48]([CH3:49])[CH3:50].[O:51]1[CH2:52][CH2:53][CH2:54][CH2:55]1>>[CH2:2]([C:3](=[O:4])[c:5]1[cH:6][c:7]([O:15][CH3:16])[c:8]([O:13][CH3:14])[c:9]([O:11][CH3:12])[cH:10]1)[S:31][c:29]1[n:28]([CH2:32][CH2:33][CH2:34][N:35]([CH2:36][CH2:37][c:38]2[n:39][cH:40][cH:41][cH:42][cH:43]2)[CH3:44])[c:27]2[c:26]([cH:25][c:24]([C:22]([N:21]([CH2:17][CH:18]([CH3:19])[CH3:20])[CH2:47][CH:48]([CH3:49])[CH3:50])=[O:23])[cH:46][cH:45]2)[n:30]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-d5d6e2fdff8d47c3b8c4418a6d3bd913
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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