Hydrochloric Acid → Hydrochloric Acid

HRID 2154441Notes

Reaction equation

HRID 2154441 reaction equation
[C:1](=[O:2])([O-:3])[O-:4].[CH3:18][c:19]1[c:20]([B:29]([OH:30])[OH:31])[cH:21][cH:22][c:23]([C:25]([F:26])([F:27])[F:28])[cH:24]1.[CH3:39][OH:40].[Cl:33][CH2:34][Cl:35].[Cl:7][c:8]1[cH:9][c:10]([C:11](=[O:12])[O:13][CH3:14])[cH:15][cH:16][n:17]1.[ClH:32].[K+:5].[K+:6].[Pd:36]([Cl:37])[Cl:38]>>[ClH:7].[c:8]1(-[c:20]2[c:19]([CH3:18])[cH:24][c:23]([C:25]([F:26])([F:27])[F:28])[cH:22][cH:21]2)[cH:9][c:10]([C:11](=[O:12])[O:13][CH3:14])[cH:15][cH:16][n:17]1

Participants

10

Reactant 8

HCID 313Hydrochloric AcidHCID 813Potassium Cation2×HCID 887MethanolHCID 6344DichloromethaneHCID 19660Carbonate IonHCID 24290Palladium ChlorideHCID 2736842Methyl 2-chloropyridine-4-carboxylateHCID 445581522-Methyl-4-(trifluoromethyl)benzeneboronic acid

Product 2

HCID 313Hydrochloric AcidHCID 66731703Methyl 2-[2-methyl-4-(trifluoromethyl)phenyl]pyridine-4-carboxylate

Sources & evidence

ORD record
ord-cbf69767adaa4ff9a701243ae87011e9
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

Loading…