Acetone → 5-chloro-N-((1-(2-(methylsulfinyl)-4-(2-oxopyridin-1(2H)-yl)phenyl)-1H-imidazol-4-yl)methyl)thiophene-2-carboxamide

HRID 2154518Notes

Reaction equation

HRID 2154518 reaction equation
[CH3:42][C:43](=[O:44])[CH3:45].[Cl:1][c:2]1[cH:3][cH:4][c:5]([C:7](=[O:8])[NH:9][CH2:10][c:11]2[n:12][cH:13][n:14](-[c:16]3[c:17]([S:29][CH3:30])[cH:18][c:19](-[n:22]4[c:23](=[O:28])[cH:24][cH:25][cH:26][cH:27]4)[cH:20][cH:21]3)[cH:15]2)[s:6]1.[OH:31][O:32][C:33]([c:34]1[cH:35][c:36]([Cl:37])[cH:38][cH:39][cH:40]1)=[O:41]>>[Cl:1][c:2]1[cH:3][cH:4][c:5]([C:7](=[O:8])[NH:9][CH2:10][c:11]2[n:12][cH:13][n:14](-[c:16]3[c:17]([S:29]([CH3:30])=[O:31])[cH:18][c:19](-[n:22]4[c:23](=[O:28])[cH:24][cH:25][cH:26][cH:27]4)[cH:20][cH:21]3)[cH:15]2)[s:6]1

Participants

4

Reactant 3

HCID 180AcetoneHCID 70297m-Chloroperbenzoic acidHCID 669741285-chloro-N-((1-(2-(methylthio)-4-(2-oxopyridin-1(2H)-yl)phenyl)-1H-imidazol-4-yl)methyl)thiophene-2-carboxamide

Product 1

HCID 247605265-chloro-N-((1-(2-(methylsulfinyl)-4-(2-oxopyridin-1(2H)-yl)phenyl)-1H-imidazol-4-yl)methyl)thiophene-2-carboxamide

Sources & evidence

ORD record
ord-729ac909492b415cbb227c6109829b67
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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