Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2154546Generated: October 26, 2026

Thionyl Chloride → 2,6-difluoro-N-(thiophen-2-ylmethyl)-nicotinamide

https://huagongshe.com/reaction/2154546

Reaction equation

Participants

RoleNameHCIDCharge
ReactantThionyl ChlorideHCID 24386—
Reactant(2-Thienylmethyl)amineHCID 34005—
Reactant2,6-Difluoropyridine-3-carboxylic acidHCID 10583070—
Product2,6-difluoro-N-(thiophen-2-ylmethyl)-nicotinamideHCID 67134517—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (4/10)
ORD IDord-777b5652992b4fa8bbbc3785043ebc1b
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (4/10)