Potassium Cation → 3-(1,1-Dioxidotetrahydro-2H-thiopyran-4-yl)-5-(1H-indazol-5-yl)-1H-indole-7-carboxamide

HRID 2154611Notes

Reaction equation

HRID 2154611 reaction equation
[Br:30][c:31]1[cH:32][c:33]2[cH:34][n:35][nH:36][c:37]2[cH:38][cH:39]1.[C:40](=[O:41])([O-:42])[O-:43].[K+:44].[K+:45].[O:1]=[S:2]1(=[O:29])[CH2:3][CH2:4][CH:5]([c:8]2[cH:9][nH:10][c:11]3[c:12]([C:26](=[O:27])[NH2:28])[cH:13][c:14]([B:17]4[O:18][C:19]([CH3:20])([CH3:21])[C:22]([CH3:23])([CH3:24])[O:25]4)[cH:15][c:16]23)[CH2:6][CH2:7]1.[O:47]1[CH2:48][CH2:49][O:50][CH2:51][CH2:52]1.[OH2:46]>>[O:1]=[S:2]1(=[O:29])[CH2:3][CH2:4][CH:5]([c:8]2[cH:9][nH:10][c:11]3[c:12]([C:26](=[O:27])[NH2:28])[cH:13][c:14](-[c:31]4[cH:32][c:33]5[cH:34][n:35][nH:36][c:37]5[cH:38][cH:39]4)[cH:15][c:16]23)[CH2:6][CH2:7]1

Participants

7

Reactant 6

HCID 813Potassium Cation2×HCID 962WaterHCID 19660Carbonate IonHCID 312751,4-DioxaneHCID 7619295-bromo-1H-indazoleHCID 593327113-(1,1-dioxidotetrahydro-2H-thiopyran-4-yl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole-7-carboxamide

Product 1

HCID 593327043-(1,1-Dioxidotetrahydro-2H-thiopyran-4-yl)-5-(1H-indazol-5-yl)-1H-indole-7-carboxamide

Sources & evidence

ORD record
ord-9fb9efc30490443c89acf49777995a01
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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