Sodium ion → 4-(4-(4-Aminophenoxy)-6-cyanoquinolin-7-yloxymethyl)-piperidine-1-carboxylic acid tert-butyl ester
Reaction equation
[C:24]([CH3:25])([CH3:26])([CH3:27])[O:28][C:29](=[O:30])[N:31]1[CH2:32][CH2:33][CH:34]([CH2:37][CH2:38][Br:39])[CH2:35][CH2:36]1.[CH3:40][N:41]([CH3:42])[CH:43]=[O:44].[H-:22].[NH2:1][c:2]1[cH:3][cH:4][c:5]([O:6][c:7]2[cH:8][cH:9][n:10][c:11]3[cH:12][c:13]([OH:19])[c:14]([C:17]#[N:18])[cH:15][c:16]23)[cH:20][cH:21]1.[Na+:23]>>[NH2:1][c:2]1[cH:3][cH:4][c:5]([O:6][c:7]2[cH:8][cH:9][n:10][c:11]3[cH:12][c:13]([O:19][CH2:37][CH:34]4[CH2:33][CH2:32][N:31]([C:29]([O:28][C:24]([CH3:25])([CH3:26])[CH3:27])=[O:30])[CH2:36][CH2:35]4)[c:14]([C:17]#[N:18])[cH:15][c:16]23)[cH:20][cH:21]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-929746f2c0b04c36b27ac400966d96ca
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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