Dichloromethane → 4'-Trifluoromethyl-biphenyl-2-carboxylic acid [4-(piperazinyl)-phenyl]-amide

HRID 2154689Notes

Reaction equation

HRID 2154689 reaction equation
[C:1]([O:2][C:3](=[O:4])[N:8]1[CH2:9][CH2:10][N:11]([c:14]2[cH:15][cH:16][c:17]([NH:20][C:21](=[O:22])[c:23]3[c:24](-[c:29]4[cH:30][cH:31][c:32]([C:35]([F:36])([F:37])[F:38])[cH:33][cH:34]4)[cH:25][cH:26][cH:27][cH:28]3)[cH:18][cH:19]2)[CH2:12][CH2:13]1)([CH3:5])([CH3:6])[CH3:7].[Cl:46][CH2:47][Cl:48].[OH:39][C:40]([C:41]([F:42])([F:43])[F:44])=[O:45]>>[NH:8]1[CH2:9][CH2:10][N:11]([c:14]2[cH:15][cH:16][c:17]([NH:20][C:21](=[O:22])[c:23]3[c:24](-[c:29]4[cH:30][cH:31][c:32]([C:35]([F:36])([F:37])[F:38])[cH:33][cH:34]4)[cH:25][cH:26][cH:27][cH:28]3)[cH:18][cH:19]2)[CH2:12][CH2:13]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 54191977HCID 54191977, compound

Product 1

HCID 112010994'-Trifluoromethyl-biphenyl-2-carboxylic acid [4-(piperazinyl)-phenyl]-amide

Sources & evidence

ORD record
ord-ad1cbdedb7e444079a3be842588f7861
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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