Tetrahydrofuran → 1-(6-Bromo-pyridin-2-ylmethyl)-3-(4-methoxy-3-methyl-benzoyl)-1H-[1,5]naphthyridin-4-one
Reaction equation
[Br:23][c:24]1[n:25][c:26]([CH2:30][Br:31])[cH:27][cH:28][cH:29]1.[CH2:42]1[O:43][CH2:44][CH2:45][CH2:46]1.[CH3:1][O:2][c:3]1[c:4]([CH3:22])[cH:5][c:6]([C:7](=[O:8])[c:9]2[cH:10][nH:11][c:12]3[cH:13][cH:14][cH:15][n:16][c:17]3[c:18]2=[O:19])[cH:20][cH:21]1.[CH3:32][SiH:33]([CH3:34])[N:35]([CH3:36])[Si:37]([CH3:38])([CH3:39])[CH3:40].[K:41]>>[CH3:1][O:2][c:3]1[c:4]([CH3:22])[cH:5][c:6]([C:7](=[O:8])[c:9]2[cH:10][n:11]([CH2:30][c:26]3[n:25][c:24]([Br:23])[cH:29][cH:28][cH:27]3)[c:12]3[cH:13][cH:14][cH:15][n:16][c:17]3[c:18]2=[O:19])[cH:20][cH:21]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-c30d6ed7986a4e0280cc8de388ba29e3
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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