Methanol → 3-(2-Amino-6-benzoylquinazolin-3(4H)-YL)-N-cyclohexyl-N-methylpropanamide

HRID 2155250Notes

Reaction equation

HRID 2155250 reaction equation
[CH3:33][CH2:34][O:35][C:36](=[O:37])[CH3:38].[CH3:39][OH:40].[N:1]#[C:2][Br:3].[NH2:4][c:5]1[c:6]([CH2:7][NH:8][CH2:9][CH2:10][C:11](=[O:12])[N:13]([CH3:14])[CH:15]2[CH2:16][CH2:17][CH2:18][CH2:19][CH2:20]2)[cH:21][c:22]([C:25]([c:26]2[cH:27][cH:28][cH:29][cH:30][cH:31]2)=[O:32])[cH:23][cH:24]1>>[NH2:1][C:2]1=[N:4][c:5]2[c:6]([cH:21][c:22]([C:25]([c:26]3[cH:27][cH:28][cH:29][cH:30][cH:31]3)=[O:32])[cH:23][cH:24]2)[CH2:7][N:8]1[CH2:9][CH2:10][C:11](=[O:12])[N:13]([CH3:14])[CH:15]1[CH2:16][CH2:17][CH2:18][CH2:19][CH2:20]1

Participants

5

Reactant 4

HCID 887MethanolHCID 8857Ethyl AcetateHCID 10476Cyanogen BromideHCID 586251113-(2-Amino-5-benzoyl-benzylamino)-N-cyclohexyl-N-methyl-propionamide

Product 1

HCID 167412383-(2-Amino-6-benzoylquinazolin-3(4H)-YL)-N-cyclohexyl-N-methylpropanamide

Sources & evidence

ORD record
ord-8d144067d56d43548d10485f06ee0a1b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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