Dichloromethane → 3-(2-Amino-propyl)-benzonitrile

HRID 2155337Notes

Reaction equation

HRID 2155337 reaction equation
[C:1]([O:2][C:3](=[O:4])[NH:7][CH:8]([CH2:9][c:10]1[cH:11][c:12]([C:16]#[N:17])[cH:13][cH:14][cH:15]1)[CH3:18])([CH3:5])([CH3:6])[CH3:19].[Cl:20][CH2:21][Cl:22].[OH:23][C:24]([C:25]([F:26])([F:27])[F:28])=[O:29]>>[NH2:7][CH:8]([CH2:9][c:10]1[cH:11][c:12]([C:16]#[N:17])[cH:13][cH:14][cH:15]1)[CH3:18]

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 69068307[2-(3-Cyano-phenyl)-1-methyl-ethyl]-carbamic acid tert-butyl ester

Product 1

HCID 575931503-(2-Amino-propyl)-benzonitrile

Sources & evidence

ORD record
ord-394ec6ce8dc048c299069b3d48790e82
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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