Cyclopropanecarbonyl chloride → tert-butyl (3RS,4RS)-4-[4-(2-cyclopropylcarbonyloxy-ethyl)-phenyl]-3-naphthalen-2-ylmethoxy-piperidine-1-carboxylate
Reaction equation
[CH:35]1([C:38](=[O:39])[Cl:40])[CH2:36][CH2:37]1.[OH:1][CH2:2][CH2:3][c:4]1[cH:5][cH:6][c:7]([CH:10]2[CH:11]([O:23][CH2:24][c:25]3[cH:26][c:27]4[cH:28][cH:29][cH:30][cH:31][c:32]4[cH:33][cH:34]3)[CH2:12][N:13]([C:16](=[O:17])[O:18][C:19]([CH3:20])([CH3:21])[CH3:22])[CH2:14][CH2:15]2)[cH:8][cH:9]1>>[O:1]([CH2:2][CH2:3][c:4]1[cH:5][cH:6][c:7]([CH:10]2[CH:11]([O:23][CH2:24][c:25]3[cH:26][c:27]4[cH:28][cH:29][cH:30][cH:31][c:32]4[cH:33][cH:34]3)[CH2:12][N:13]([C:16](=[O:17])[O:18][C:19]([CH3:20])([CH3:21])[CH3:22])[CH2:14][CH2:15]2)[cH:8][cH:9]1)[C:38]([CH:35]1[CH2:36][CH2:37]1)=[O:39]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-bd208c6aff6645f3b32d44b3bf96cac9
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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