Hydrochloric Acid → 4-Bromo-1H-indole-2-carboxylic acid {1-[2-(3-hydroxy-8-aza-bicyclo[3.2.1]oct-8-yl)-ethyl]-piperidin-4-yl}-amide

HRID 215549Notes

Reaction equation

HRID 215549 reaction equation
[Br:1][c:2]1[c:3]2[cH:4][c:5]([C:11](=[O:12])[OH:13])[nH:6][c:7]2[cH:8][cH:9][cH:10]1.[ClH:14].[ClH:15].[ClH:16].[NH2:17][CH:18]1[CH2:19][CH2:20][N:21]([CH2:24][CH2:25][N:26]2[CH:27]3[CH2:28][CH:29]([OH:34])[CH2:30][CH:31]2[CH2:32][CH2:33]3)[CH2:22][CH2:23]1>>[Br:1][c:2]1[c:3]2[cH:4][c:5]([C:11](=[O:13])[NH:17][CH:18]3[CH2:19][CH2:20][N:21]([CH2:24][CH2:25][N:26]4[CH:27]5[CH2:28][CH:29]([OH:34])[CH2:30][CH:31]4[CH2:32][CH2:33]5)[CH2:22][CH2:23]3)[nH:6][c:7]2[cH:8][cH:9][cH:10]1

Participants

4

Reactant 3

HCID 313Hydrochloric Acid3×HCID 40426044-bromo-1H-indole-2-carboxylic acidHCID 596001408-[2-(4-Aminopiperidin-1-yl)ethyl]-8-azabicyclo[3.2.1]octan-3-ol

Product 1

HCID 668414474-Bromo-1H-indole-2-carboxylic acid {1-[2-(3-hydroxy-8-aza-bicyclo[3.2.1]oct-8-yl)-ethyl]-piperidin-4-yl}-amide

Sources & evidence

ORD record
ord-e20c020ffaea4cef96b671a71bb8a85b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

Loading…