Piperidine → 4-Piperidin-1-yl-6-trifluoromethyl-2-[4-(3-trifluoromethyl-pyridin-2-yl)-piperazin-1-yl]-1-(2-trimethylsilanyl-ethoxymethyl)-1H-benzoimidazole
Reaction equation
[Br:1][c:2]1[cH:3][c:4]([C:35]([F:36])([F:37])[F:38])[cH:5][c:6]2[n:7]([CH2:27][O:28][CH2:29][CH2:30][Si:31]([CH3:32])([CH3:33])[CH3:34])[c:8]([N:11]3[CH2:12][CH2:13][N:14]([c:17]4[n:18][cH:19][cH:20][cH:21][c:22]4[C:23]([F:24])([F:25])[F:26])[CH2:15][CH2:16]3)[n:9][c:10]12.[CH2:39]1[CH2:40][CH2:41][NH:42][CH2:43][CH2:44]1>>[c:2]1([N:42]2[CH2:41][CH2:40][CH2:39][CH2:44][CH2:43]2)[cH:3][c:4]([C:35]([F:36])([F:37])[F:38])[cH:5][c:6]2[n:7]([CH2:27][O:28][CH2:29][CH2:30][Si:31]([CH3:32])([CH3:33])[CH3:34])[c:8]([N:11]3[CH2:12][CH2:13][N:14]([c:17]4[n:18][cH:19][cH:20][cH:21][c:22]4[C:23]([F:24])([F:25])[F:26])[CH2:15][CH2:16]3)[n:9][c:10]12Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-42ce146f07894e7387d476accfb80eff
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
Loading…