p-Toluenesulfonic acid → N-(2,6-difluorophenyl)-5-(3-{2-[(2-(ethyloxy)-5-methyl-4-{4-[2-(methylsulfonyl)ethyl]-1-piperazinyl}phenyl)amino]-4-pyrimidinyl}imidazo[1,2-a]pyridin-2-yl)-2-[(1-methylethyl)oxy]benzamide
Reaction equation
[CH3:38][c:39]1[c:40]([N:49]2[CH2:50][CH2:51][N:52]([CH2:55][CH2:56][S:57](=[O:58])(=[O:59])[CH3:60])[CH2:53][CH2:54]2)[cH:41][c:42]([O:46][CH2:47][CH3:48])[c:43]([NH2:45])[cH:44]1.[Cl:1][c:2]1[n:3][cH:4][cH:5][c:6](-[c:8]2[c:9](-[c:17]3[cH:18][cH:19][c:20]([O:34][CH:35]([CH3:36])[CH3:37])[c:21]([C:22](=[O:23])[NH:24][c:25]4[c:26]([F:32])[cH:27][cH:28][cH:29][c:30]4[F:31])[cH:33]3)[n:10][c:11]3[n:12]2[cH:13][cH:14][cH:15][cH:16]3)[n:7]1.[F:72][CH2:73][C:74]([F:75])([F:76])[OH:77].[c:61]1([CH3:62])[cH:63][cH:64][c:65]([S:66]([OH:67])(=[O:68])=[O:69])[cH:70][cH:71]1>>[c:2]1([NH:45][c:43]2[c:42]([O:46][CH2:47][CH3:48])[cH:41][c:40]([N:49]3[CH2:50][CH2:51][N:52]([CH2:55][CH2:56][S:57](=[O:58])(=[O:59])[CH3:60])[CH2:53][CH2:54]3)[c:39]([CH3:38])[cH:44]2)[n:3][cH:4][cH:5][c:6](-[c:8]2[c:9](-[c:17]3[cH:18][cH:19][c:20]([O:34][CH:35]([CH3:36])[CH3:37])[c:21]([C:22](=[O:23])[NH:24][c:25]4[c:26]([F:32])[cH:27][cH:28][cH:29][c:30]4[F:31])[cH:33]3)[n:10][c:11]3[n:12]2[cH:13][cH:14][cH:15][cH:16]3)[n:7]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-cfbd18dc5cfd42908919c4efccc6ff5e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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