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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2155825Generated: November 3, 2026

Water → 2-[(t-Butyldimethylsilyloxy)methyl]-4-[(2,5-difluorophenyl)hydroxymethyl]-5-methylpyridine

https://huagongshe.com/reaction/2155825

Reaction equation

Participants

RoleNameHCIDCharge
ReactantWaterHCID 962—
ReactantDiethyl EtherHCID 3283—
ReactantHexaneHCID 8058—
Reactant2,5-DifluorobenzaldehydeHCID 137663—
Reactant4-Bromo-2-[(t-butyldimethylsilyloxy)methyl]-5-methylpyridineHCID 23114823—
ReactantButyllithiumHCID 178418339—
Product2-[(t-Butyldimethylsilyloxy)methyl]-4-[(2,5-difluorophenyl)hydroxymethyl]-5-methylpyridineHCID 23114729—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (4/10)
ORD IDord-b31f4e4863ed4f2ba41b4aacdfe8c051
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (4/10)