Hydrochloric Acid → 6-[1-(4-Methoxy-3-propoxy-benzyl)-piperidin-4-ylamino]-4-trifluoromethyl-nicotinic acid
Reaction equation
[CH2:1]([O:2][c:3]1[cH:4][c:5]([CH2:30][N:8]2[CH2:9][CH2:10][CH:11]([NH:14][c:15]3[n:16][cH:17][c:18]([C:19](=[O:20])[OH:21])[c:22]([C:24]([F:25])([F:26])[F:27])[cH:23]3)[CH2:12][CH2:13]2)[cH:6][cH:7][c:28]1[OH:29])[CH3:31].[CH3:34][O:35][C:36](=[O:37])[c:38]1[c:39]([C:40]([F:41])([F:42])[F:43])[cH:44][c:45]([NH:46][CH:47]2[CH2:48][CH2:49][NH:50][CH2:51][CH2:52]2)[n:53][cH:54]1.[CH3:55][O:56][c:57]1[c:58]([O:65][CH2:66][CH2:67][CH3:68])[cH:59][c:60]([CH:61]=[O:62])[cH:63][cH:64]1.[ClH:32].[ClH:33]>>[N:8]1([CH2:61][c:60]2[cH:59][c:58]([O:65][CH2:66][CH2:67][CH3:68])[c:57]([O:56][CH3:55])[cH:64][cH:63]2)[CH2:9][CH2:10][CH:11]([NH:14][c:15]2[n:16][cH:17][c:18]([C:19](=[O:20])[OH:21])[c:22]([C:24]([F:25])([F:26])[F:27])[cH:23]2)[CH2:12][CH2:13]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-b98d883c762348ff9122adc9dc525a9c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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