反应详情

温度

85 °C

A mixture of resorcinol (20 g), ethyl benzoylacetate (23.8 mL) and O-phosphoric acid (130 mL) was heated at 85° C. (care!) for 1 hr. The solution was cooled, poured onto H2O, extracted 3×EtOAc/THF, washed twice with H2O, and then twice with brine. The organic phase was dried and evaporated. Trituration with Et2O followed by filtration afforded the title compound as a solid.

1. temperatureThe solution was cooled
2. additionpoured onto H2O
3. extractionextracted 3×EtOAc/THF
4. washwashed twice with H2O
5. customThe organic phase was dried
6. customevaporated
7. filtrationTrituration with Et2O followed by filtration