Dichloromethane → 7-Acetyl-2,7-diaza-spiro[4.5]decane-2-carboxylic acid tert-butyl ester

HRID 2157116Notes

Reaction equation

HRID 2157116 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][C:10]2([CH2:11][CH2:12]1)[CH2:13][NH:14][CH2:15][CH2:16][CH2:17]2.[CH3:18][C:19](=[O:20])[O:21][C:22](=[O:23])[CH3:24].[CH3:25][CH2:26][N:27]([CH2:28][CH3:29])[CH2:30][CH3:31].[Cl:32][CH2:33][Cl:34]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][C:10]2([CH2:11][CH2:12]1)[CH2:13][N:14]([C:19]([CH3:18])=[O:20])[CH2:15][CH2:16][CH2:17]2

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 7918Acetic AnhydrideHCID 8471TriethylamineHCID 45934304tert-Butyl 2,7-diazaspiro[4.5]decane-2-carboxylate

Product 1

HCID 687714687-Acetyl-2,7-diaza-spiro[4.5]decane-2-carboxylic acid tert-butyl ester

Sources & evidence

ORD record
ord-75046b6cfbce46f8a80136494807d559
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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