Ammonia → 1-{2-[3-(3,4,5-Trichlorophenyl)-3-(trifluoromethyl)-pyrrolidin-1-yl]-4-(trifluoromethyl)-1,3-thiazol-5-yl}methanamine
Reaction equation
[CH3:35][S:36](=[O:37])(=[O:38])[Cl:39].[CH3:43][OH:44].[Cl:1][c:2]1[cH:3][c:4]([C:10]2([C:26]([F:27])([F:28])[F:29])[CH2:11][N:12]([c:15]3[s:16][c:17]([CH2:24][OH:25])[c:18]([C:20]([F:21])([F:22])[F:23])[n:19]3)[CH2:13][CH2:14]2)[cH:5][c:6]([Cl:9])[c:7]1[Cl:8].[NH3:41].[O:30]1[CH2:31][CH2:32][CH2:33][CH2:34]1.[OH2:40].[OH2:42]>>[Cl:1][c:2]1[cH:3][c:4]([C:10]2([C:26]([F:27])([F:28])[F:29])[CH2:11][N:12]([c:15]3[s:16][c:17]([CH2:24][NH2:41])[c:18]([C:20]([F:21])([F:22])[F:23])[n:19]3)[CH2:13][CH2:14]2)[cH:5][c:6]([Cl:9])[c:7]1[Cl:8]Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-08dbb393e3b84842a8f3f96bbb4c8e1a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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