Chloroform → 7-(4-Ethoxycarbonylpiperidin-4-ylmethoxy)-1,2,3,4-tetrahydroisoquinoline-2-carboxylic acid benzyl ester
Reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][C:9](=[O:10])[N:11]1[CH2:12][c:13]2[cH:14][c:15]([O:21][CH2:22][C:23]3([C:36](=[O:37])[O:38][CH2:39][CH3:40])[CH2:24][CH2:25][N:26]([C:29]([O:30][C:31]([CH3:32])([CH3:33])[CH3:34])=[O:35])[CH2:27][CH2:28]3)[cH:16][cH:17][c:18]2[CH2:19][CH2:20]1.[CH:48]([Cl:49])([Cl:50])[Cl:51].[OH:41][C:42]([C:43]([F:44])([F:45])[F:46])=[O:47]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][C:9](=[O:10])[N:11]1[CH2:12][c:13]2[cH:14][c:15]([O:21][CH2:22][C:23]3([C:36](=[O:37])[O:38][CH2:39][CH3:40])[CH2:24][CH2:25][NH:26][CH2:27][CH2:28]3)[cH:16][cH:17][c:18]2[CH2:19][CH2:20]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-23467835155d4071b597a6d577157f7d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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