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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2157431Generated: October 27, 2026

Tetrahydrofuran → Methyl 2-[2-methyl-4-[3-[4-(2-pyridin-2-ylethynyl)phenyl]-3-[4-(trifluoromethyl)phenyl]prop-2-enoxy]phenoxy]acetate

https://huagongshe.com/reaction/2157431

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantTriethylamineHCID 8471—
ReactantCopper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 24350—
ReactantEthynylpyridineHCID 137268—
ReactantMethyl 2-[4-[3-(4-iodophenyl)-3-[4-(trifluoromethyl)phenyl]prop-2-enoxy]-2-methylphenoxy]acetateHCID 91270331—
ReactantHCID 178420554HCID 178420554—
ProductMethyl 2-[2-methyl-4-[3-[4-(2-pyridin-2-ylethynyl)phenyl]-3-[4-(trifluoromethyl)phenyl]prop-2-enoxy]phenoxy]acetateHCID 91332689—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (4/10)
ORD IDord-35c443e8c5474b44bc7f1cd63615d2a5
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (4/10)