Ethyl Acetate → (-)-6-chloro-4-(4-fluorophenyl)-4-propyl-3-(2,2,2-trifluoroethyl)-3,4-dihydroquinazolin-2(1H)-one

HRID 2157479Notes

Reaction equation

HRID 2157479 reaction equation
[CH2:1]([CH:2]=[CH2:3])[C:4]1([c:21]2[cH:22][cH:23][c:24]([F:27])[cH:25][cH:26]2)[N:5]([CH2:16][C:17]([F:18])([F:19])[F:20])[C:6](=[O:15])[NH:7][c:8]2[cH:9][cH:10][c:11]([Cl:14])[cH:12][c:13]21.[CH3:28][CH2:29][O:30][C:31](=[O:32])[CH3:33]>>[CH2:1]([CH2:2][CH3:3])[C:4]1([c:21]2[cH:22][cH:23][c:24]([F:27])[cH:25][cH:26]2)[N:5]([CH2:16][C:17]([F:18])([F:19])[F:20])[C:6](=[O:15])[NH:7][c:8]2[cH:9][cH:10][c:11]([Cl:14])[cH:12][c:13]21

Participants

3

Reactant 2

HCID 8857Ethyl AcetateHCID 118538114-allyl-6-chloro-4-(4-fluorophenyl)-3-(2,2,2-trifluoroethyl)-3,4-dihydroquinazolin-2(1H)-one

Product 1

HCID 11853812(-)-6-chloro-4-(4-fluorophenyl)-4-propyl-3-(2,2,2-trifluoroethyl)-3,4-dihydroquinazolin-2(1H)-one

Sources & evidence

ORD record
ord-a4bf685d177b485480d48e87475768d5
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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