Water → 2-Cyclopropyl-8-fluoro-4-methyl-3-(4-pyrazol-1-ylbenzyl)quinolin-5-ol
Reaction equation
[C:33](=[O:34])([O-:35])[O-:36].[CH:27]1([B:30]([OH:31])[OH:32])[CH2:28][CH2:29]1.[Cl:1][c:2]1[n:3][c:4]2[c:5]([F:26])[cH:6][cH:7][c:8]([OH:25])[c:9]2[c:10]([CH3:24])[c:11]1[CH2:12][c:13]1[cH:14][cH:15][c:16](-[n:19]2[n:20][cH:21][cH:22][cH:23]2)[cH:17][cH:18]1.[Cs+:37].[Cs+:38].[O:39]1[CH2:40][CH2:41][O:42][CH2:43][CH2:44]1.[OH2:45]>>[c:2]1([CH:27]2[CH2:28][CH2:29]2)[n:3][c:4]2[c:5]([F:26])[cH:6][cH:7][c:8]([OH:25])[c:9]2[c:10]([CH3:24])[c:11]1[CH2:12][c:13]1[cH:14][cH:15][c:16](-[n:19]2[n:20][cH:21][cH:22][cH:23]2)[cH:17][cH:18]1Participants
7
Sources & evidence
- ORD record
- ord-b6237433bf8c490bb82b40095c6cf5a4
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
Loading…