HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methylamine → N,1-Dimethyl-5-methoxy-3-(1-methylethoxy)-1H-indole-2-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methylamine | HCID 6329 | — |
| Reactant | Ammonium Hydroxide | HCID 14923 | — |
| Reactant | 5-Methoxy--methyl-3-(1-methylethoxy)-1H-indole-2-carboxylic acid | HCID 13885799 | — |
| Product | N,1-Dimethyl-5-methoxy-3-(1-methylethoxy)-1H-indole-2-carboxamide | HCID 19933216 | 45% |
Reaction Steps
Prepared from 5-methoxy-1-methyl-3-(1-methylethoxy)-1H-indole-2-carboxylic acid by the procedure of Example 1 with 40% aqueous methylamine solution substituted for ammonium hydroxide. Yield 45% after recrystallization from hexane; mp 85°-86° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05424329 |
| Source dataset | uspto-grants-1995_06 |
| ORD ID | ord-82db390998834a639cb2e2540efcb206 |
| Source note | uspto-grants-1995_06 |