Dimethyl Sulfoxide → Ethyl 9-fluoro-8-[4-(4-fluorophenyl)piperazin-1-yl]-4-methyl-1-oxo-1,4-dihydrobenzo[f] [1,7]naphthyridine-2-carboxylate
Reaction equation
[CH3:38][S:39](=[O:40])[CH3:41].[F:1][c:2]1[cH:3][c:4]2[c:5]([c:6]3[c:7](=[O:20])[c:8]([C:15](=[O:16])[O:17][CH2:18][CH3:19])[cH:9][n:10]([CH3:14])[c:11]3[cH:12][n:13]2)[cH:21][c:22]1[F:23].[F:24][c:25]1[cH:26][cH:27][c:28]([N:31]2[CH2:32][CH2:33][NH:34][CH2:35][CH2:36]2)[cH:29][cH:30]1.[OH2:37]>>[c:2]1([N:34]2[CH2:33][CH2:32][N:31]([c:28]3[cH:27][cH:26][c:25]([F:24])[cH:30][cH:29]3)[CH2:36][CH2:35]2)[cH:3][c:4]2[c:5]([c:6]3[c:7](=[O:20])[c:8]([C:15](=[O:16])[O:17][CH2:18][CH3:19])[cH:9][n:10]([CH3:14])[c:11]3[cH:12][n:13]2)[cH:21][c:22]1[F:23]Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-32cf10e9c73a4b21bc2abb8a0883fbcd
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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