Tetrahydrofuran → (3-(tert-butyldimethylsilyloxy)-5-ethyl-2-fluorophenyl)(2-methyl-5-phenyl-2H-1,2,4-triazol-3-yl)methanol
Reaction equation
[C:18]([CH3:19])([CH3:20])([CH3:21])[Si:22]([O:23][c:24]1[c:25]([F:34])[c:26]([CH:27]=[O:28])[cH:29][c:30]([CH2:32][CH3:33])[cH:31]1)([CH3:35])[CH3:36].[CH2:13]([Li:14])[CH2:15][CH2:16][CH3:17].[CH2:37]1[O:38][CH2:39][CH2:40][CH2:41]1.[CH3:1][n:2]1[n:3][c:4](-[c:7]2[cH:8][cH:9][cH:10][cH:11][cH:12]2)[n:5][cH:6]1>>[CH3:1][n:2]1[n:3][c:4](-[c:7]2[cH:8][cH:9][cH:10][cH:11][cH:12]2)[n:5][c:6]1[CH:27]([c:26]1[c:25]([F:34])[c:24]([O:23][Si:22]([C:18]([CH3:19])([CH3:20])[CH3:21])([CH3:35])[CH3:36])[cH:31][c:30]([CH2:32][CH3:33])[cH:29]1)[OH:28]Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-64568f832f6543559a78c6351f526ec9
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
Loading…