Sodium ion → tert-Butyl 4-(1-hydroxy-3-methoxy-3-oxo-1-(2-pivalamidopyridin-3-yl)propan-2-yl)piperidine-1-carboxylate
Reaction equation
[CH2:1]([Li:2])[CH2:3][CH2:4][CH3:5].[CH3:6][O:7][C:8]([CH2:9][CH:10]1[CH2:11][CH2:12][N:13]([C:16](=[O:17])[O:18][C:19]([CH3:20])([CH3:21])[CH3:22])[CH2:14][CH2:15]1)=[O:23].[CH:26](=[O:27])[c:28]1[c:29]([NH:34][C:35]([C:36]([CH3:37])([CH3:38])[CH3:39])=[O:40])[n:30][cH:31][cH:32][cH:33]1.[H-:24].[Na+:25].[O:41]1[CH2:42][CH2:43][CH2:44][CH2:45]1>>[CH3:6][O:7][C:8]([CH:9]([CH:10]1[CH2:11][CH2:12][N:13]([C:16](=[O:17])[O:18][C:19]([CH3:20])([CH3:21])[CH3:22])[CH2:14][CH2:15]1)[CH:26]([OH:27])[c:28]1[c:29]([NH:34][C:35]([C:36]([CH3:37])([CH3:38])[CH3:39])=[O:40])[n:30][cH:31][cH:32][cH:33]1)=[O:23]Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-64db97ee9d84498994196b2fc2f271f8
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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