Water → 2-chloro-N-cyclopropyl-7-phenyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-amine

HRID 2158702Notes

Reaction equation

HRID 2158702 reaction equation
[CH3:23][N:24]1[CH2:25][CH2:26][CH2:27][C:28]1=[O:29].[CH:18]1([NH2:21])[CH2:19][CH2:20]1.[Cl:1][c:2]1[n:3][c:4]([Cl:17])[c:5]2[c:6]([n:7]1)[CH:8]([c:11]1[cH:12][cH:13][cH:14][cH:15][cH:16]1)[CH2:9][CH2:10]2.[OH2:22]>>[Cl:1][c:2]1[n:3][c:4]([NH:21][CH:18]2[CH2:19][CH2:20]2)[c:5]2[c:6]([n:7]1)[CH:8]([c:11]1[cH:12][cH:13][cH:14][cH:15][cH:16]1)[CH2:9][CH2:10]2

Participants

5

Reactant 4

HCID 962WaterHCID 13387N-methyl-2-pyrrolidoneHCID 69828CyclopropylamineHCID 580754632,4-Dichloro-7-phenyl-6,7-dihydro-5H-cyclopenta[D]pyrimidine

Product 1

HCID 580758182-chloro-N-cyclopropyl-7-phenyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-amine

Sources & evidence

ORD record
ord-ad0ba4214dbc48e2bae36a406fe78df2
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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