Dichloromethane → 4-Amino-1-hydroxy-N-(1-phenylethyl)cyclohexanecarboxamide

HRID 2158857Notes

Reaction equation

HRID 2158857 reaction equation
[C:8]([O:9][C:10](=[O:11])[NH:14][CH:15]1[CH2:16][CH2:17][C:18]([C:21]([NH:22][CH:23]([CH3:24])[c:25]2[cH:26][cH:27][cH:28][cH:29][cH:30]2)=[O:31])([OH:32])[CH2:19][CH2:20]1)([CH3:12])([CH3:13])[CH3:33].[Cl:34][CH2:35][Cl:36].[OH:1][C:2]([C:3]([F:4])([F:5])[F:6])=[O:7]>>[NH2:14][CH:15]1[CH2:16][CH2:17][C:18]([C:21]([NH:22][CH:23]([CH3:24])[c:25]2[cH:26][cH:27][cH:28][cH:29][cH:30]2)=[O:31])([OH:32])[CH2:19][CH2:20]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 58292016[4-Hydroxy-4-(1-phenyl-ethylcarbamoyl)-cyclohexyl]-carbamic acid tert-butyl ester

Product 1

HCID 582917954-Amino-1-hydroxy-N-(1-phenylethyl)cyclohexanecarboxamide

Sources & evidence

ORD record
ord-1f9ef8e54dc6474a9a163895c7e9db04
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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