Potassium Cation → 5,6-dihydro-2-[4-[3-(4-piperidinyl)propoxy]phenyl]-4H-1,3-oxazine

HRID 2159105Notes

Reaction equation

HRID 2159105 reaction equation
[CH3:30][CH:31]([OH:32])[CH3:33].[K+:29].[O:1]1[C:2]([c:7]2[cH:8][cH:9][c:10]([O:11][CH2:12][CH2:13][CH2:14][CH:15]3[CH2:16][CH2:17][N:18]([C:21]([O:22][CH2:23][CH3:24])=[O:25])[CH2:19][CH2:20]3)[cH:26][cH:27]2)=[N:3][CH2:4][CH2:5][CH2:6]1.[OH-:28]>>[O:1]1[C:2]([c:7]2[cH:8][cH:9][c:10]([O:11][CH2:12][CH2:13][CH2:14][CH:15]3[CH2:16][CH2:17][NH:18][CH2:19][CH2:20]3)[cH:26][cH:27]2)=[N:3][CH2:4][CH2:5][CH2:6]1

Participants

5

Reactant 4

HCID 813Potassium CationHCID 961HydroxideHCID 3776IsopropanolHCID 14989203ethyl 4-[3-[4-(5,6-dihydro-4H-1,3-oxazin-2-yl)phenoxy]propyl]-1-piperidinecarboxylate

Product 1

HCID 149892045,6-dihydro-2-[4-[3-(4-piperidinyl)propoxy]phenyl]-4H-1,3-oxazine

Sources & evidence

ORD record
ord-2610e36feac949d79209afa20d1e90c0
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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