Ammonia → 4-Chloro-5-(4-ethylphenyl)-6-(2-fluorophenyl)furo[2,3-d]pyrimidine

HRID 2159340Notes

Reaction equation

HRID 2159340 reaction equation
[CH2:1]([CH3:2])[c:3]1[cH:4][cH:5][c:6](-[c:9]2[c:10](-[c:19]3[c:20]([F:25])[cH:21][cH:22][cH:23][cH:24]3)[o:11][c:12]3[n:13][cH:14][nH:15][c:16](=[O:18])[c:17]23)[cH:7][cH:8]1.[NH3:31].[OH2:32].[P:26]([Cl:27])([Cl:28])([Cl:29])=[O:30]>>[CH2:1]([CH3:2])[c:3]1[cH:4][cH:5][c:6](-[c:9]2[c:10](-[c:19]3[c:20]([F:25])[cH:21][cH:22][cH:23][cH:24]3)[o:11][c:12]3[n:13][cH:14][n:15][c:16]([Cl:28])[c:17]23)[cH:7][cH:8]1

Participants

5

Reactant 4

HCID 222AmmoniaHCID 962WaterHCID 24813Phosphorus oxychlorideHCID 58016929HCID 58016929, compound

Product 1

HCID 580167964-Chloro-5-(4-ethylphenyl)-6-(2-fluorophenyl)furo[2,3-d]pyrimidine

Sources & evidence

ORD record
ord-2807c585fa754acc95b88b414248a386
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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