Acetonitrile → 4-(3-Fluoro-2,4-dimethoxyphenylethynyl)-1-(4-methoxybenzyl)-1H-pyrazole

HRID 2159424Notes

Reaction equation

HRID 2159424 reaction equation
[C:13](#[CH:14])[c:15]1[cH:16][n:17][n:18]([CH2:20][c:21]2[cH:22][cH:23][c:24]([O:27][CH3:28])[cH:25][cH:26]2)[cH:19]1.[CH3:29][C:30]#[N:31].[Cu:32][I:33].[F:1][c:2]1[c:3]([O:11][CH3:12])[c:4]([I:10])[cH:5][cH:6][c:7]1[O:8][CH3:9]>>[F:1][c:2]1[c:3]([O:11][CH3:12])[c:4]([C:14]#[C:13][c:15]2[cH:16][n:17][n:18]([CH2:20][c:21]3[cH:22][cH:23][c:24]([O:27][CH3:28])[cH:25][cH:26]3)[cH:19]2)[cH:5][cH:6][c:7]1[O:8][CH3:9]

Participants

5

Reactant 4

HCID 6342AcetonitrileHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 509982281,3-Dimethoxy-2-fluoro-4-iodobenzeneHCID 574219374-Ethynyl-1-(4-methoxybenzyl)-1H-pyrazole

Product 1

HCID 574219494-(3-Fluoro-2,4-dimethoxyphenylethynyl)-1-(4-methoxybenzyl)-1H-pyrazole

Sources & evidence

ORD record
ord-04c3f3a43b2246b9b0e34a3b0c275b57
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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