Potassium Cation → 2-tert-Butyl-4-cyclobutyl-6-{4-[3-(pyrimidin-4-yloxy)-propyl]-piperazin-1-yl}-pyrimidine

HRID 2159442Notes

Reaction equation

HRID 2159442 reaction equation
[C:14]([CH3:15])([CH3:16])([CH3:17])[c:18]1[n:19][c:20]([CH:34]2[CH2:35][CH2:36][CH2:37]2)[cH:21][c:22]([N:24]2[CH2:25][CH2:26][N:27]([CH2:30][CH2:31][CH2:32][Cl:33])[CH2:28][CH2:29]2)[n:23]1.[C:8](=[O:9])([O-:10])[O-:11].[CH3:38][N:39]([CH3:40])[CH:41]=[O:42].[K+:12].[K+:13].[OH:1][c:2]1[n:3][cH:4][n:5][cH:6][cH:7]1>>[O:1]([c:2]1[n:3][cH:4][n:5][cH:6][cH:7]1)[CH2:32][CH2:31][CH2:30][N:27]1[CH2:26][CH2:25][N:24]([c:22]2[cH:21][c:20]([CH:34]3[CH2:35][CH2:36][CH2:37]3)[n:19][c:18]([C:14]([CH3:15])([CH3:16])[CH3:17])[n:23]2)[CH2:29][CH2:28]1

Participants

6

Reactant 5

HCID 813Potassium Cation2×HCID 6228DimethylformamideHCID 19660Carbonate IonHCID 666731042-tert-Butyl-4-[4-(3-chloro-propyl)-piperazin-1-yl]-6-cyclobutyl-pyrimidineHCID 178516514HCID 178516514, compound

Product 1

HCID 116687102-tert-Butyl-4-cyclobutyl-6-{4-[3-(pyrimidin-4-yloxy)-propyl]-piperazin-1-yl}-pyrimidine

Sources & evidence

ORD record
ord-77885aa569b94401b8d602551595d39d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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