Dichloromethane → 4-chloro-6-methoxy-7-[2-(N-methyl-N-prop-2-yn-1-ylamino)ethoxy]quinazoline
Reaction equation
[CH2:54]([Cl:55])[Cl:56].[CH3:46][N:47]([CH2:48][C:49]#[CH:50])[CH2:51][CH2:52][OH:53].[Cl:13][c:14]1[n:15][cH:16][n:17][c:18]2[cH:19][c:20]([OH:26])[c:21]([O:24][CH3:25])[cH:22][c:23]12.[O:1]=[C:2]([O:3][CH2:4][CH3:5])[N:6]=[N:7][C:8]([O:9][CH2:10][CH3:11])=[O:12].[c:27]1([P:28]([c:29]2[cH:30][cH:31][cH:32][cH:33][cH:34]2)[c:35]2[cH:36][cH:37][cH:38][cH:39][cH:40]2)[cH:41][cH:42][cH:43][cH:44][cH:45]1>>[Cl:13][c:14]1[n:15][cH:16][n:17][c:18]2[cH:19][c:20]([O:26][CH2:52][CH2:51][N:47]([CH3:46])[CH2:48][C:49]#[CH:50])[c:21]([O:24][CH3:25])[cH:22][c:23]12Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-b3e70ddba6854b61beb79b28c39520e2
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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